Health Sciences Center - Kuwait University

Telephone no.: Office: 24636505&nbsp;&nbsp;&nbsp; Mobile: 66529609
Fax: 25332719
Field of Specialization: Molecular Microbiology and Immunology
Research Interests: Molecular biology and immunology of infectious diseases with specific reference to diagnosis and identification of vaccine candidates against tuberculosis and other mycobacterial diseases<?xml:namespace prefix = "o" ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p>
Publications&nbsp;(for the last 5 years):
1.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Siddique I, Al-Qabandi A, Al-Ali J, Alazmi W, Memon A, Mustafa AS, Junaid TA (2014). Association between Helicobacter pylori genotypes and severity of chronic gastritis, peptic ulcer disease and gastric mucosal interleukin-8 levels: Evidence from a study in the Middle East. Gut Pathogen&nbsp; 26;6:41.<o:p></o:p>
2.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2014). T-helper 1, T-helper 2, pro-inflammatory and anti-inflammatory cytokines in tuberculosis. <o:p></o:p>
International Journal of Pharma Medicine and Biological Sciences 3, 1-14.<o:p></o:p>
3.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2014). Characterization of a cross-reactive, immunodominant and HLA-promiscuous epitope of Mycobacterium tuberculosis-specific major antigenic protein PPE68. PLoS One 9(8):e103679.<o:p></o:p>
4.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Amoudy HA, Ebrahimi BH, Mustafa AS (2014). Immune responses against Mycobacterium tuberculosis-specific proteins PE35 and CFP10 in mice immunized with recombinant Mycobacterium vaccae. Saudi Med J 35:350-359.<o:p></o:p>
5.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2014). The future of&nbsp; Mycobacterium tuberculosis-specific antigens/peptides in tuberculin skin testing for the diagnosis of tuberculosis. J Mycobac Dis 4:3.<o:p></o:p>
6.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2013). Diagnostic and Vaccine Potentials of ESAT-6 Family Proteins encoded&nbsp; by M. tuberculosis genomic regions absent in M. bovis BCG. J Mycobac Dis 3:129.<o:p></o:p>
7.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2013). In silico analysis and experimental validation of&nbsp; Mycobacterium tuberculosis-specific proteins and peptides of Mycobacterium tuberculosis for immunological diagnosis and vaccine development.&nbsp; Medical Principles and Practice 22 (Suppl 1): 43-51.<o:p></o:p>
8.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Shaban K, Amoudy HA, Mustafa AS (2013). Cellular immune responses to recombinant Mycobacterium bovis BCG constructs expressing major antigens of region of difference 1 of&nbsp; Mycobacterium tuberculosis. Clinical Vaccine Immunology 20:1230-1237.<o:p></o:p>
9.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Albert MJ, Mustafa AS, Islam A, Haridas S (2013) Oral immunization with cholera toxin provides protection against Campylobacter jejuni in an adult mouse intestinal colonization model. MBio 4. pii: e00246-13.<o:p></o:p>
10.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2012). What's New in the Development of Tuberculosis Vaccines. Medical Principles and Practice 21:195-196.<o:p></o:p>
11.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2012). Proteins and peptides encoded by M. tuberculosis-specific genomic regions for immunological diagnosis of tuberculosis. Journal of Mycobacterial Diseases 2:e114.<o:p></o:p>
12.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Al-Attiyah R, El-Shazly A, Mustafa AS (2012). Comparative analysis of spontaneous and mycobacterial antigen-induced secretion of Th1, Th2 and pro-inflammatory cytokines by peripheral blood mononuclear cells of tuberculosis patients. Scandinavian Journal of Immunology 75:623-632.<o:p></o:p>
13.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Babiker FA, Hoteit LJ, Joseph S, Mustafa AS, a Juggi JS (2012). The role of 17-beta estradiol in ischemic preconditioning protection of the heart.&nbsp; Experimental and Clinical Cardiology 17:95-100.<o:p></o:p>
14.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hanif SNM, Al-Attiyah R, Mustafa AS (2011). The natural expression of genes encoding major antigens of Rd1 and Rd9 in M. tuberculosis and other mycobacteria. Mycobacterial Diseases 1:105. <o:p></o:p>
15.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hanif SN, Al-Attiyah R, Mustafa AS (2011). Cellular immune responses in mice induced by M. tuberculosis PE35-DNA vaccine construct. Scandinavian Journal of Immunology 74:554-60.<o:p></o:p>
16.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2011). Comparative evaluation of MPT83 (Rv2873) for T helper-1 cell reactivity and identification of HLA-promiscuous peptides: studies in M. bovis BCG-vaccinated healthy subjects. Clinical and Vaccine Immunology 18:1752-9.<o:p></o:p>
17.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Juggi JS, Hoteit LJ, Babiker FA, Joseph H and Mustafa AS (2011). Protective role of normothermic, hyperthermic and estrogen preconditioning and pretreatment on tumor necrosis factor-alpha-induced damage. Experimental and Clinical Cardiology 16: e5-e10.<o:p></o:p>
18.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS, Al-Saidi F, El-Shamy ASM and Al-Attiyah R (2011). Cytokines in response to proteins predicted in genomic regions of difference of Mycobacterium tuberculosis. Microbiology and Immunology, 55:267-278. <o:p></o:p>
19.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Al-Khodari NY, Al-Attiyah R, and Mustafa AS (2011). Identification, diagnostic potential and natural expression of immunodominant seroreactive peptides encoded by five Mycobacterium tuberculosis-specific genomic regions. Clinical and Vaccine Immunology 18:477-482.<o:p></o:p>
20.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hanif SNM, Al-Attiyah R and Mustafa AS (2010). DNA vaccine constructs expressing Mycobacterium tuberculosis-specific genes induce immune responses. Scandinavian Journal of Immunology 72:408-415.<o:p></o:p>
21.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2010). In silico binding predictions for identification of HLA-DR-promiscuous regions and epitopes of Mycobacterium tuberculosis protein MPT64 (Rv1980c), and their recognition by human Th1 cells.&nbsp; Medical Principles and Practice 19:367-372.<o:p></o:p>
22.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Al-Attiyah R, Mustafa AS (2010). Characterization of human cellular immune responses to Mycobacterium tuberculosis proteins encoded by genes predicted in RD15 genomic region that is absent in Mycobacterium bovis BCG. FEMS Immunology and Medical Microbiology 59:177-187.<o:p></o:p>
23.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hanif SNM, Al-Attiyah R and Mustafa AS (2010). Molecular cloning, expression, purification and immunological characterization of three low molecular weight proteins encoded by genes in genomic regions of difference of Mycobacterium tuberculosis. Scandinavian Journal of Immunology 71:353-361.<o:p></o:p>
24.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Hanif SNM, Al-Attiyah R and Mustafa AS (2010). Species-specific antigenic Mycobacterium tuberculosis proteins as tested by delayed-type hypersensitivity response. International Journal of Tuberculosis and Lung Diseases 14:489-494.<o:p></o:p>
25.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Mustafa AS (2010). Cell mediated immunity assays identify proteins of diagnostic and vaccine potential from genomic regions of difference of Mycobacterium tuberculosis. Kuwait Medical Journal 42:98-105.
26.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Mustafa AS, Shaban F (2010). Mapping of Th1-cell epitope regions of Mycobacterium tuberculosis protein MPT64 (Rv1980c) using synthetic peptides and T-cell lines from M. tuberculosis-infected healthy humans. Medical Principles and Practice 19:122-128.